EPA Tier I Endocrine Disruptor Screening Assays

The U.S. EPA, through the Food Quality Protection Act, now requires testing of chemicals at the Tier I level to evaluate their potential for endocrine disruption. Wildlife International, Ltd. conducts the appropriate ecotoxicity testing required for Tier I.

Fish Short-Term Reproduction Assay/Amphibian Metamorphosis Assay

Wildlife International, Ltd. has over 30 years of experience providing comprehensive environmental toxicology testing programs industry-wide. One area of specialization is the development and performance of tests designed to evaluate the potential for a chemical to impact the endocrine systems of aquatic organisms. Our experience includes:

Participation in validation of Tier I and Tier II endocrine assays for EPA
Conduct of several developmental studies with amphibians (Xenopus laevis) with multiple endocrine endpoints
Conduct and validation of multiple fish reproduction screening assays
In-depth involvement with and technical contributions to scientific and regulatory forums to help ensure that assays of scientific validity are developed

The future of your material may rest with the results of Tier I testing. Our experience and involvement in guideline development and method optimization makes Wildlife International, Ltd. the ideal partner for providing the ecotoxicity testing required for EPA’s Tier I endocrine disruptor screening assays.

EPA Tier 1 Endocrine Disruptor Screening Assays Sheet:
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